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HomeMIT 7.91J Foundations of Computational and Systems BiologyLecture 5: Library Complexity and Short Read Alignment (Mapping)
Lecture 5: Library Complexity and Short Read Alignment (Mapping)
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Lecture 6: Genome Assembly
Description: Prof. Gifford talks about library complexity as it relates to genome sequencing. He explains how to create a full-text minute-size (FM) index, which involves a Burrows-Wheeler transform (BWT). He ends with how to deal with the problem of mismatching.
Instructor: Prof. David Gifford