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HomeMIT 7.91J Foundations of Computational and Systems BiologyLecture 4: Comparative Genomic Analysis of Gene Regulation

Lecture 4: Comparative Genomic Analysis of Gene Regulation

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Lecture 5: Library Complexity and Short Read Alignment (Mapping)

Description: Prof. Burge discusses comparative genomics. He begins with a review of global alignment of protein sequences, then talks about Markov models, the Jukes-Cantor model, and Kimura models. He discusses types of selection: natural, negative, and positive.

Instructor: Christopher Burge