
Molecular Biology – Part 3: RNA Processing and Translation
An in-depth adventure through RNA Processing and Translation. Strengthen your scientific thinking and biological experimental design skills.

Course Information
Certificate Track
Learn for Free
About this Course
In Part 3 of the 7.28x Molecular Biology Series, you will explore translation of mRNA to protein, a key part of the central dogma of biology. Do you know how RNA structure and mechanisms of turnover affect the outcome of translation? Although not explicitly named in the central dogma, the properties and processing mechanisms of RNA molecules strongly influence gene expression.
Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?
Take a behind-the-scenes look at modern molecular biology, from the classic experimental events that identified the proteins and elements involved in translation to cutting-edge assays that apply the power of genome sequencing. Do you feel confident in your ability to design molecular biology experiments and interpret data from them? We designed the assessments in this course to build your experimental design and data analysis skills.
Explore the limits of our current knowledge about the translation and RNA turnover machinery and mechanisms and join us in 7.28.3x Molecular Biology: RNA Processing and Translation.
What you'll learn
- How to compare and contrast translation in bacteria and eukaryotes.
- How to describe the interactions between proteins and RNA in regulating translation.
- How to differentiate mechanisms of RNA turnover.
- How to analyze protein structures to infer functional information.
- How to design the best experiment to test a hypothesis.
- How to interpret data from translation and RNA processing experiments.
Prerequisites
7.00x Introduction to Biology, 7.03x Genetics, 7.05x Biochemistry or similar (biochemistry, molecular biology, and genetics), 7.28.1x, and 7.28.2x Molecular Biology or similar (advanced understanding of the central dogma).
Meet your instructors
Stephen Bell
HHMI Investigator; Professor of Biology at MIT
Steve Bell is a Professor of Biology in the Department of Biology at MIT and an HHMI Investigator. Steve and his lab study the regulation of eukaryotic replication using biochemical, genetic, and molecular biology approaches. He has received the institute-wide Everett Moore Baker Memorial Teaching Award as well as a School of Science Teaching Prize for Excellence in Undergraduate Education. Along with Tania, Steve co-authored a popular molecular biology textbook with James Watson.